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EFFECT OF CHEMORADIATION THERAPY ON THE DEVELOPING DENTITION

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Abstract

ÇÏ¾Ç ÁÂÃøºÎÀ§ÀÇ È¾¹®±ÙÀ°Á¾À¸·Î 2³âµ¿¾ÈÀÇ È­Çпä¹ý°ú 6ÁÖ°£ÀÇ ¹æ»ç¼±¿ä¹ýÀ¸·Î Ä¡·á¸¦ ¹Þ¾Ò°í, ÀÌ¿¡ µû¸¥ ÈÄÀ¯ÁõÀ¸·Î Ä¡¾ÆÀÇ ¹ßÀ°Àå¾Ö¸¦ µ¿¹ÝÇÑ 8¼¼ ȯ¾Æ¿¡ ´ëÇØ, ÀÓ»óÀû, ¹æ»ç¼±ÇÐÀûÀ¸·Î °üÂûÀ» ½ÃÇàÇÏ°í, Ä¡·áÇÑ °á°ú ´ÙÀ½À» º¸°íÇÏ´Â ¹ÙÀÌ´Ù.
1. ±¸°­³» ¼Ò°ßÀ¸·Î¼­ ¸ÍÃâÇÑ ¿µ±¸Ä¡ÀÇ °æ¹ÌÇÑ ¹ý¶ûÁú Çü¼ººÎÀü°ú Ä¡¾Æ¿ì½ÄÀÌ °üÂûµÇ¾úÀ¸¸ç, ÇÏ¾Ç ÁÂÃø ºÎÀ§ÀÇ ¹Ì¸ÍÃâµÈ Á¦ 1´ë±¸Ä¡·Î ÀÎÇØ ¼öÁ÷°í°æÀÌ »ó½ÇµÇ¾î °ú°³±³ÇÕÀÌ Çü¼ºµÇ¾ú´Ù.
2. ¹æ»ç¼±ÇÐÀûÀ¸·Î ¸ÍÃâÇÑ ¿µ±¸Ä¡ÀÇ Ä¡±ÙÀº ªÀº Ä¡±Ù¿¡¼­ºÎÅÍ ¹«Çü¼ºÁõ¿¡ À̸£±â±îÁö ´Ù¾çÇÑ Ä¡±ÙÀÇ ¹ßÀ°Àå¾Ö¸¦ º¸¿´À¸¸ç, ¹Ì¸ÍÃâ »óÅÂÀÎ Á¦ 2¼Ò±¸Ä¡¿Í Á¦ 2´ë±¸Ä¡´Â ¿Ö¼ÒÄ¡³ª Çü¼ººÎÀüÀÇ ¼Ò°ßÀ» º¸¿´´Ù.
3. Ä¡·á´Â º¸Á¸Ä¡·á ¹× Àú¼®È¸È­ ¼Ò°ßÀ» º¸ÀÌ´Â ¿µ±¸Ä¡¸¦ À§ÇØ ºÒ¼ÒµµÆ÷¸¦ ½ÃÇàÇÏ¿´°í, ÇâÈÄ ÀûÀýÇÑ ¼öÁ÷°í°æÀÇ È¸º¹°ú ½É¹ÌÀû °³¼±À» À§ÇÑ Æ÷°ýÀûÀÎ º¸Ã¶Ä¡·á°¡ ¼öÇàµÇ¾î¾ß ÇÒ °ÍÀ¸·Î »ç·áµÈ´Ù.

Chemoradiation therapy used on pediatric oncology patients often causes dental developmental anomalies that affect future dental care. Defects noted include tooth and root agenesis, root thin¡©ing and shortening, and localized enamel defects. The effect of radiotherapy usually are confined to the radiation site, but the effects of chemotherapy may be more wide spread because of its sys¡©temic distribution and structures and organs unrelated to the primary tumor may be affected. Many pediatric cancers are treated with a combination of radiation and multiagent chemotherapy to cre¡©ate synergic and additive effects.
Dental treatment affected by chemoradiation damage to developing teeth includes orthodon¡©tic tooth movement, prosthetic abutment considerations, periodontal health, space maintenance, requirements for home fluoride regimens to protect hypomineralized areas, restoration options for hypoplastic/hypomineralized teeth, and endodontic procedures.
The following case demonstrate chemoradiation therapy effects on the dental development.

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È­Çйæ»ç¼±¿ä¹ý;Ä¡±Ù¹«Çü¼ºÁõ;¹ßÀ°ÀÌ»ó;chemoradiation therapy;developing dentition;root agenesis

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